KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DLAT
All Species:
35.45
Human Site:
S214
Identified Species:
48.75
UniProt:
P10515
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10515
NP_001922.2
647
68997
S214
S
A
Q
A
P
G
S
S
Y
P
P
H
M
Q
V
Chimpanzee
Pan troglodytes
XP_522180
647
68973
S214
S
A
Q
A
P
G
S
S
Y
P
P
H
M
Q
V
Rhesus Macaque
Macaca mulatta
XP_001107013
647
68918
S214
S
A
Q
A
P
G
S
S
Y
P
P
H
M
Q
V
Dog
Lupus familis
XP_546524
647
68802
S214
P
A
Q
A
P
G
S
S
Y
P
T
H
M
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMF4
642
67923
S213
S
A
S
A
P
G
S
S
Y
P
T
H
M
Q
I
Rat
Rattus norvegicus
P08461
632
67147
S204
S
A
S
A
P
G
S
S
Y
P
V
H
M
Q
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509202
536
56600
T120
P
A
L
S
P
T
M
T
M
G
T
V
Q
R
W
Chicken
Gallus gallus
XP_417933
681
72018
S243
S
P
Q
A
P
G
S
S
Y
P
P
H
M
Q
V
Frog
Xenopus laevis
NP_001082239
628
66845
T191
A
V
Q
A
P
G
S
T
Y
P
N
H
M
K
I
Zebra Danio
Brachydanio rerio
NP_997832
652
69250
S214
A
P
Q
V
P
G
S
S
Y
P
P
H
M
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609118
512
54233
V98
T
M
E
R
G
S
I
V
S
W
E
K
K
E
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19749
507
53448
T93
S
P
T
M
E
L
G
T
V
V
S
W
Q
K
K
Sea Urchin
Strong. purpuratus
XP_001190217
487
52117
Q73
T
V
V
R
W
E
K
Q
V
G
D
Q
L
N
D
Poplar Tree
Populus trichocarpa
XP_002303212
512
55370
I98
T
E
A
C
L
G
N
I
A
R
W
L
K
K
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q5M729
539
58449
E125
S
L
S
P
T
M
T
E
G
N
I
A
R
W
L
Baker's Yeast
Sacchar. cerevisiae
P12695
482
51800
I68
Q
L
S
P
G
E
V
I
A
E
I
E
T
D
K
Red Bread Mold
Neurospora crassa
P20285
458
48601
P44
V
K
M
P
A
L
S
P
T
M
T
S
G
G
I
Conservation
Percent
Protein Identity:
100
99.2
98.1
89.4
N.A.
85.6
85.1
N.A.
70.3
72
72.8
71.9
N.A.
42
N.A.
41.7
39.8
Protein Similarity:
100
99.2
98.6
92.8
N.A.
90.2
89.6
N.A.
74.5
78.4
82.6
78.9
N.A.
53.9
N.A.
55
54.1
P-Site Identity:
100
100
100
86.6
N.A.
80
80
N.A.
13.3
93.3
60
73.3
N.A.
0
N.A.
6.6
0
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
33.3
93.3
86.6
86.6
N.A.
20
N.A.
20
13.3
Percent
Protein Identity:
36.3
N.A.
N.A.
38.6
33.5
36.6
Protein Similarity:
50.2
N.A.
N.A.
53
48.2
48.8
P-Site Identity:
6.6
N.A.
N.A.
6.6
0
6.6
P-Site Similarity:
26.6
N.A.
N.A.
20
0
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
42
6
48
6
0
0
0
12
0
0
6
0
0
0
% A
% Cys:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
6
0
0
6
6
% D
% Glu:
0
6
6
0
6
12
0
6
0
6
6
6
0
6
6
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
12
59
6
0
6
12
0
0
6
6
6
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
53
0
0
0
% H
% Ile:
0
0
0
0
0
0
6
12
0
0
12
0
0
0
24
% I
% Lys:
0
6
0
0
0
0
6
0
0
0
0
6
12
24
12
% K
% Leu:
0
12
6
0
6
12
0
0
0
0
0
6
6
0
6
% L
% Met:
0
6
6
6
0
6
6
0
6
6
0
0
53
0
0
% M
% Asn:
0
0
0
0
0
0
6
0
0
6
6
0
0
6
0
% N
% Pro:
12
18
0
18
59
0
0
6
0
53
30
0
0
0
0
% P
% Gln:
6
0
42
0
0
0
0
6
0
0
0
6
12
42
0
% Q
% Arg:
0
0
0
12
0
0
0
0
0
6
0
0
6
6
0
% R
% Ser:
48
0
24
6
0
6
59
48
6
0
6
6
0
0
0
% S
% Thr:
18
0
6
0
6
6
6
18
6
0
24
0
6
0
0
% T
% Val:
6
12
6
6
0
0
6
6
12
6
6
6
0
0
36
% V
% Trp:
0
0
0
0
6
0
0
0
0
6
6
6
0
6
6
% W
% Tyr:
0
0
0
0
0
0
0
0
53
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _